Principal Scientist (Analytical Sciences)

Location: Rensselaer, New York, United States; onsite Monday–Friday, 8:00 a.m.–4:30 p.m.

Salary: $108,000–$176,000 annually

Company

hirify.global is a biotechnology company that discovers, develops, and commercializes medicines for serious diseases.

What you will do

• Develop, optimize, validate, transfer, and manage analytical methods for raw materials and products, focusing on siRNA oligonucleotides and peptide therapeutics.
• Design protocols for assay qualification and validation and ensure methods support GMP release testing, characterization, and stability evaluation.
• Evaluate and implement analytical technologies including LCMS, capillary electrophoresis, ion-pair reversed-phase HPLC, hybridization-based assays, and peptide mapping.
• Transfer control testing procedures to Quality Control and prepare transfer plans, training materials, and acceptance criteria.
• Lead troubleshooting, OOS/OOT investigations, deviation root-cause analyses, and customer complaint assessments.
• Present technical findings, author SOPs and lifecycle documents, mentor junior scientists, and represent Analytical Sciences on cross-functional teams.

Requirements

• PhD in Chemistry, Biochemistry, Biology, or a related field.
• 3+ years of relevant industry experience in analytical development and Quality Control method lifecycle management.
• Demonstrated experience developing and validating methods for siRNA oligonucleotides and peptide therapeutics.
• Hands-on proficiency with LCMS/MS, capillary electrophoresis, ion-pair reversed-phase HPLC, peptide mapping, and oligonucleotide characterization assays.
• Experience with method transfer, troubleshooting, OOS/OOT investigations, technical writing, data integrity, and cross-functional collaboration.
• Ability to work onsite in Rensselaer, New York, Monday–Friday from 8:00 a.m. to 4:30 p.m.

Culture & Benefits

• Inclusive workplace with equal employment opportunity practices.
• Comprehensive rewards package that may include annual bonuses, equity awards, retirement benefits, health and wellness programs, insurance, paid time off, and family support benefits.
• Work is structured around onsite collaboration for many roles.