Senior Medical Director, Clinical Development (Autoimmune and Inflammatory Diseases)

Location: Hybrid in Boston, Massachusetts, with at least two on-site days per week, currently Tuesday and Wednesday. Additional on-site attendance may be required based on business needs.

Salary: $293,000–$379,500 per year, with a potential discretionary annual bonus and long-term incentive award.

Company

hirify.global is a clinical-stage biotechnology company developing precision therapies for autoimmune and inflammatory diseases.

What you will do

• Lead clinical development strategies, integrated development plans, and medical decision-making for assigned pipeline assets across Phase I–III.
• Design, author, and review clinical protocols, investigator brochures, informed consent documents, and clinical sections of regulatory submissions.
• Provide medical oversight of clinical trials, including safety monitoring, SAE assessment, protocol deviation review, and benefit-risk evaluation.
• Represent assigned programs in FDA and EMA interactions, prepare briefing documents, and respond to health authority questions.
• Direct cross-functional clinical program teams across Clinical Operations, Regulatory Affairs, Translational Medicine, Biostatistics, Pharmacovigilance, and Medical Affairs.
• Build relationships with key opinion leaders, principal investigators, and academic medical centers while mentoring junior physicians and contributing to portfolio decisions.

Requirements

• MD or DO required; board certification or clinical training in rheumatology, nephrology, immunology, or a related specialty is strongly preferred.
• At least 10 years of combined clinical and pharmaceutical or biotechnology industry experience, including preferably 5 years in clinical development.
• Deep expertise in autoimmune disease, immunology, and inflammation; rheumatology experience is preferred.
• Experience leading Phase I–III clinical programs, including protocol development, medical monitoring, and regulatory submissions.
• Ability to identify and mitigate clinical, operational, and regulatory risks across multinational clinical programs.
• Strong scientific communication, leadership, and clinical document authoring skills, including protocols, clinical study reports, regulatory briefing documents, and manuscripts.

Nice to have

• Additional advanced degree such as a PhD, MPH, or MBA.
• Experience leading first-in-human studies, proof-of-concept readouts, pivotal trial initiation, and regulatory submissions.

Culture & Benefits

• Hybrid work arrangement with flexible scheduling.
• Health and wellness coverage, with structure and premiums varying by country.
• Paid time off, public holidays, and additional leave according to local requirements.
• Opportunity to work in a growth-stage biotechnology environment focused on autoimmune and inflammatory disease therapies.