Principal Biostatistician (Biostatistics)

Location: Permanent homebased in Frankfurt, Hesse, Germany

Company

IQVIA provides clinical research services, commercial insights, and healthcare intelligence for the life sciences and healthcare industries.

What you will do

• Serve as the primary statistical lead and Biostatistics point of contact for clinical trial teams.
• Provide independent statistical guidance across the design, execution, and analysis of late-phase clinical studies.
• Lead discussions on endpoints, analysis methods, estimands, risk mitigation, and regulatory expectations.
• Author Statistical Analysis Plans and perform or oversee scientifically rigorous statistical analyses.
• Conduct sample size calculations using SAS or R and justify design assumptions.
• Direct statistical programming activities, review outputs, and collaborate with clinical, data management, medical writing, and programming partners.

Requirements

• Advanced degree in Biostatistics, Statistics, or a related field; a PhD is preferred, while a Master's degree is accepted with significant experience.
• Independent study statistician experience in Phase II/III clinical trials.
• Hands-on experience with clinical outcomes studies, including cardiovascular events, symptomatic endpoints, and quality-of-life measures.
• Expertise in complex statistical methods, including time-to-event analyses, MMRM, longitudinal models, and estimand-based approaches.
• Proficiency in SAS; working knowledge of R is advantageous.
• Ability to guide cross-functional teams and communicate statistical concepts clearly to non-statistical stakeholders.

Nice to have

• Pharmaceutical industry experience; CRO experience is a plus.
• Experience with regulatory submissions and interaction with health authorities.
• Experience with R, CRM systems, or advanced analytical tools.

Culture & Benefits

• Permanent homebased work arrangement.
• Full-time employment.
• Work within a global clinical research and healthcare intelligence organization.
• Focus on integrity and truthful, complete application information.