Supervising Principal Scientist, Process Development (Cell Therapy)

Location: South San Francisco, CA, United States; on-site

Company

hirify.global develops an advanced cell therapy manufacturing platform.

What you will do

• Lead multifaceted process development efforts to improve the cell therapy manufacturing platform.
• Manage technology transfer, data reviews, and program governance with external partners.
• Develop program timelines, gap assessments, development plans, statements of work, test plans, and protocols.
• Manage, mentor, and provide technical training to junior team members.
• Present technical and organizational updates and proposals to Technical Operations leadership.
• Evaluate new technologies and author or review technical documents, procedures, reports, and presentations.

Requirements

• Bachelor’s, Master’s, or PhD in Bioengineering, Chemical Engineering, Biology, Biochemistry, or a related field.
• 6–20 years of process development experience in the cell and gene therapy field.
• Subject-matter expertise in T cell, HSC, iPSC, or other immune cell therapy modalities.
• Hands-on experience with Miltenyi Prodigy, Lonza Cocoon, Xuri Wave, or comparable commercial cell processing instruments.
• Knowledge of cell editing and payload delivery technologies, including LVV, RVV, LNP, CRISPR, TALENs, and ZFNs.
• Strong communication skills and the ability to present scientific results to technical and non-technical audiences.

Nice to have

• Knowledge of cGMP regulations and ICH guidelines.
• Self-awareness, integrity, authenticity, enthusiasm, and a growth mindset.

Culture & Benefits

• Fast-paced, mission-driven work environment.
• Cross-functional collaboration across Process Development, Analytical Development, MSAT, Quality, Manufacturing, Alliance Management, and Engineering.
• Leveling is based on experience, education, and demonstrated knowledge during the interview process.