Scientist (Non-Viral Gene Delivery)

Location: San Francisco Bay Area; on-site

Salary: $120,000–$165,000 annually plus equity

Company

hirify.global is a frontier research lab developing high-bandwidth brain-computer interfaces that integrate biological systems with artificial intelligence.

What you will do

• Develop and evaluate non-viral gene delivery approaches for molecular biosensors and neural activity actuators.
• Formulate, adapt, and characterize lipid nanoparticles, polymeric nanoparticles, and other delivery vehicles for central nervous system applications.
• Define efficacy and tolerability criteria and develop assays and readouts to measure delivery performance.
• Design, run, and interpret in vivo studies in rodents and, where appropriate, large animal models.
• Evaluate delivery technologies combined with ultrasound-mediated blood-brain barrier opening, including durability and repeat dosing.
• Collaborate with protein engineers, cell and synthetic biologists, data scientists, physicists, and neurobiologists while driving projects independently.

Requirements

• Ph.D. or equivalent experience leading research projects end-to-end in bioengineering, chemical engineering, drug delivery, neuroscience, molecular biology, or a related field.
• Hands-on experience with non-viral delivery vehicles, including lipid or polymeric nanoparticles.
• Expertise in developing, optimizing, or critically evaluating gene delivery modalities.
• Experience designing and executing in vivo studies and interpreting delivery and expression results.
• Experience advancing a delivery technology through preclinical translation or into the clinic.
• Ability to work independently and collaborate effectively across scientific disciplines.

Nice to have

• Experience sourcing, evaluating, or in-licensing delivery technologies through external collaborators.
• Familiarity with CMC, scale-up, or GMP manufacturing considerations for nanoparticle formulations.
• Experience with repeat dosing, immunogenicity, microfluidic formulation, or analytical characterization.
• Experience with ligand or antibody conjugation, focused ultrasound blood-brain barrier opening, or large animal models.

Culture & Benefits

• Work on multidisciplinary frontier biotechnology and neurotechnology problems.
• Collaborate across molecular engineering, neuroscience, bioengineering, and in vivo research.
• Opportunity to recruit and mentor research associates as projects expand.
• Compensation includes equity.