Senior Scientist, Bioinformatics (NGS)

Location: Fully remote; can be performed from anywhere. Occasional domestic and international travel of approximately 0%–15% is expected.

Salary: $127,000–$165,500 annual

Company

hirify.global is a global biopharmaceutical company developing treatments for patients with serious and rare diseases.

What you will do

• Design, develop, and maintain bioinformatics pipelines for WGS, WES, bulk and single-cell transcriptomics, spatial transcriptomics, and epigenomics.
• Analyze biological datasets and prepare interpretation reports for comparability studies, AAV characterization, and potency cell line characterization.
• Develop bioinformatics platforms for biomarker discovery, disease-mechanism research, patient stratification, and therapeutic-response analysis.
• Apply statistical rigor to experimental design and result interpretation, including Bayesian approaches.
• Present findings to technical and non-technical stakeholders and contribute to publications, regulatory submissions, and internal reports.
• Lead projects independently, mentor associate scientists, and support pipeline qualification and validation.

Requirements

• PhD with 5+ years of industry experience, Master’s with 6 years, or Bachelor’s with 8 years of industry experience.
• Experience analyzing NGS data, including PacBio and Element Biosciences platforms.
• Strong understanding of statistics, including Bayesian methods, across multiple data types.
• Production-quality programming experience with Python, R, JavaScript, Go, or Rust, including collaborative Git-based development.
• Experience with Python testing frameworks, cloud environments such as AWS, Azure, or Google Cloud, and Docker.
• Experience with workflow management systems such as Snakemake, Nextflow, or CWL.

Nice to have

• Degree in bioinformatics, computational biology, genomics, molecular biology, or a related field.
• Experience releasing software for use by others and working with SQL databases.
• Familiarity with machine learning algorithms and single-cell or spatial sequencing tools such as Seurat or Scanpy.
• Knowledge of FDA or EMA regulatory requirements, FAIR data principles, bioinformatics standards, GAMP5, or risk-based software validation.

Culture & Benefits

• Fully remote work with support for purposeful in-person collaboration.
• Medical, dental, and vision coverage, mental health support, wellbeing reimbursement, and an Employee Assistance Program.
• Paid time off, fertility and family-forming benefits, caregiver support, and flexible work schedules.
• 401(k) with company match, annual equity awards, ESPP, and company-paid life and disability insurance.
• Learning programs, mentorship, employee resource groups, service programs, and volunteer opportunities.