PhD Position Structural Biology (Neuronal Synapse)
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Описание вакансии
TL;DR
PhD Position Structural Biology (Neuronal Synapse): Investigating the molecular mechanisms of synapse assembly and disassembly using cryo-electron tomography and advanced microscopy with an accent on structural biology and neuroscience. Focus on developing a cryo-ET FIB SEM workflow, visualizing nanoscale synaptic architecture, and determining high-resolution structures of synaptic cell-adhesion molecules.
Location: Must be based in or relocate to Delft, the Netherlands
Salary: €3,059–€3,881 gross per month
Company
Delft University of Technology () is a leading international research university combining science, engineering, and design to address global challenges in energy, climate, health, and digital society.
What you will do
- Develop and implement a cryo-ET FIB SEM workflow for synaptic assemblies.
- Visualize the nanoscale architecture of neuronal synapses.
- Determine high-resolution structures of synaptic cell-adhesion molecule pairs.
- Conduct confirmative structure-function studies in primary neurons.
- Collaborate with the PI and group members to drive scientific research.
- Develop scientific independence through the Doctoral Education Programme.
Requirements
- M.Sc. degree in nanobiology, biochemistry, biophysics, structural biology, or a related field.
- Fluent in English (written and spoken).
- Experience with electron microscopy or structural biology approaches.
- Strong interest in learning cryo-EM and cryo-ET techniques.
- Ability to work in an international research environment.
Nice to have
- Prior experience with cryo-EM or cryo-ET.
Culture & Benefits
- 4-year PhD employment contract with initial 1.5-year assessment.
- Comprehensive benefits including 8% holiday allowance and 8.3% end-of-year bonus.
- Access to state-of-the-art cryo-electron microscopy and light microscopy facilities.
- Supportive international research environment with mentorship and training.
- Relocation support via the Coming to Delft Service and Dual Career Programme.
- Flexible work schedules and discounts on health insurance.
Hiring process
- Submission of motivation letter and detailed CV.
- Selection process including reference checks.
- Knowledge security risk assessment during final stages.
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