Histology / Immunohistochemistry Scientist

Location: 100% onsite in Boston, Massachusetts, 02108, US

Salary: $114,200

Company

hirify.global provides staffing and temporary assignment services for scientific and technical roles.

What you will do

• Optimize, validate, and execute immunohistochemistry assays with appropriate controls.
• Design and perform histology experiments using human and mouse tissue samples for preclinical and clinical research programs.
• Process, embed, section, stain, and image tissue samples while building and managing an archival FFPE specimen library.
• Characterize and validate compound and antibody activity using histology-based biomarkers.
• Analyze and interpret histology and imaging data and communicate findings to project teams and stakeholders.
• Maintain experimental documentation, troubleshoot assays, and collaborate across scientific disciplines.

Requirements

• Associate, bachelor’s, or master’s degree with at least 1 year of industry or academic experience.
• Strong knowledge of immunohistochemistry and in situ hybridization, including method development, optimization, and troubleshooting.
• Experience processing and embedding formalin-fixed paraffin-embedded (FFPE) tissues and sectioning FFPE and frozen tissue blocks.
• Experience performing immunohistochemistry, immunofluorescence, and RNAscope assays manually and/or with automated staining platforms.
• Interest in or understanding of oncology, immuno-oncology, and/or immunology.

Nice to have

• Image analysis experience using open-source or commercial software, plus image acquisition and basic microscopy skills.
• Strong data analysis skills, including practical knowledge of statistics.
• Experience with LIMS systems.
• Experience with multiplex staining and histology platforms such as Phenocycler, COMET, or similar systems.
• Experience with automated immunostainers such as Leica Bond or similar platforms, whole-slide imaging, tissue processing and embedding, and microtome or cryostat sectioning.

Culture & Benefits

• 1-year assignment with the possibility of extension.
• Independent work combined with proactive collaboration in a multidisciplinary research environment.
• For temporary assignments lasting 13 weeks or longer: major medical, dental, vision, 401(k), and statutory sick pay where required.
• Reasonable accommodations are available during the employment process.