Director, Clinical Scientist (Respiratory)

Location: Remote in the U.S. Somerville, MA / Andover, MA headquarters; travel to HQ based on business needs.

Base salary: $186,000–$279,000 per year, plus annual bonus, equity compensation, and benefits.

Company

hirify.global is a clinical-stage generative biology company using machine learning and large-scale experimentation to design proteins and develop protein-based medicines.

What you will do

• Serve as clinical science lead for Phase 2 and 3 respiratory studies in asthma and/or COPD.
• Support study execution, protocol compliance, timelines, regulatory requirements, site engagement, and investigator support.
• Design clinical protocols and supporting documents, including clinical study plans, data review plans, CRFs, database designs, statistical analysis plans, IBs, CSRs, and briefing books.
• Review and interpret clinical data with cross-functional teams and external partners to support data quality, participant safety, and protocol compliance.
• Track milestones, identify risks to timelines and data integrity, implement mitigation strategies, and serve as a scientific contact for CROs and vendors.
• Contribute to governance meetings, inspection readiness, publication plans, clinical development plans, TPPs, risk-benefit assessments, and oversight committees such as DSMBs and Endpoint Adjudication Committees.

Requirements

• Advanced degree such as PhD, PharmD, MD, MS, or PMP.
• 9+ years of industry experience in clinical development, including direct late-stage respiratory experience in asthma and/or COPD studies.
• Strong knowledge of clinical research methodologies, regulatory guidelines, and GCP.
• Demonstrated ability to lead clinical science strategy and execution in late-stage trials.
• Excellent analytical, communication, and cross-functional collaboration skills.
• Prior experience authoring clinical protocols, CSRs, and regulatory documents.

Nice to have

• Experience with both small-molecule and biologic modalities.
• Familiarity with AI/ML-driven drug discovery platforms.
• Previous involvement in BLA or MAA submissions.

Culture & Benefits

• Collaborative, inclusive, and high-performing cross-functional environment.
• Ownership of clinical execution with emphasis on quality, rigor, transparency, and technical precision.
• Mentorship and coaching opportunities, with clear data-driven communication and decision-making.
• Annual bonus, equity compensation, and competitive benefits package.
• Travel to headquarters may be required based on business needs.