Process Modeling (Protein/Antigen) Principal Data Scientist

Location: Waltham, MA; US and Puerto Rico residents only

Salary: $122,250.00–$176,583.33 annually

Company

hirify.global is an R&D-driven, AI-powered biopharmaceutical company developing medicines and vaccines through immunoscience, data, and digital research.

What you will do

• Lead the development and deployment of AI, machine learning, mechanistic, and hybrid models for recombinant protein vaccine process development and manufacturing.
• Apply advanced analytics to identify critical process parameters, predict product quality, improve yield, and optimize process performance.
• Develop models for CHO cell culture, baculovirus and insect cell expression systems, cell line development, and downstream purification operations.
• Build digital twins, simulation tools, and decision-support frameworks for process optimization, scale-up, technology transfer, and lifecycle management.
• Collaborate with process development, analytical sciences, manufacturing, and digital teams to turn process data and knowledge into actionable insights.
• Provide scientific leadership and mentorship in AI, machine learning, data science, and process modeling.

Requirements

• Ph.D. in Chemical Engineering, Bioengineering, Biotechnology, Computational Biology, Data Science, Applied Mathematics, or a related scientific discipline.
• At least 2 years of relevant experience in the pharmaceutical industry.
• Fluent English required.

Nice to have

• Experience applying data science, machine learning, and process modeling in biopharmaceutical, biologics, vaccine, or related development environments, including recombinant protein production and manufacturing.
• Expertise in AI, machine learning, multivariate data analysis, mechanistic and hybrid modeling, digital twins, process simulation, Bayesian optimization, and Design of Experiments.
• Experience with CHO cell culture, baculovirus expression systems, protein purification, and/or cell line development.
• Proficiency with Python, R, MATLAB, JMP, gPROMS, GoSilico, or equivalent scientific computing and modeling platforms.
• Strong scientific leadership, problem-solving, communication, and cross-functional collaboration skills.

Culture & Benefits

• Full-time role in a supportive, future-focused, and culturally inclusive environment.
• Opportunities for promotion, lateral career moves, and international development.
• Health and wellbeing benefits, including healthcare, prevention and wellness programs, and at least 14 weeks of gender-neutral parental leave.
• Employee rewards and benefits are provided in line with the position and demonstrated experience.
• Opportunity to work with diverse science, clinical, manufacturing, and digital teams on AI-enabled drug and vaccine development.