Director, Nonclinical Toxicology Operations (Biotech)

Location: Brisbane, California, United States — onsite presence expected

Salary: $220,700–$252,667 per year

Company

hirify.global is a clinical-stage biopharmaceutical company developing targeted protein degradation medicines for cancer and inflammatory diseases through an AI-integrated discovery engine.

What you will do

• Plan and coordinate GLP and non-GLP in vivo and in vitro safety studies, including exploratory toxicology, dose range finding, repeat-dose toxicology, safety pharmacology, and genetic toxicology.
• Select and manage CROs and specialty vendors, including bids, contracts, work orders, change orders, budgets, invoices, and forecasts.
• Build integrated study timelines, track milestones and deliverables, coordinate reviews, and escalate risks affecting schedules or regulatory submissions.
• Manage discovery and development programs from late lead optimization through candidate selection, IND-enabling studies, and IND filing.
• Integrate chemistry, DMPK, pharmacology, toxicology, CMC, and regulatory plans into critical paths, dashboards, risk registers, and resource views.
• Lead project meetings, portfolio reviews, governance updates, scenario planning, and continuous improvement of project management practices.

Requirements

• M.S. or Ph.D. in toxicology, pharmacology, biology, chemistry, pharmaceutical sciences, or a related life sciences discipline.
• Typically 10+ years of relevant biotech or pharmaceutical experience with ownership of multidisciplinary project management.
• Experience managing CROs and external vendors, including contracting, budget tracking, and performance management.
• Direct experience supporting and coordinating IND-enabling activities, with working knowledge of small-molecule development, nonclinical safety assessment, and GLP requirements.
• Proficiency with integrated timelines, critical path analysis, resource planning, and project management tools such as MS Project, Smartsheet, or Planisware.
• Based in Brisbane, California, with onsite presence required to support laboratory and program teams.

Nice to have

• Formal project management credential such as PMP.
• Experience in targeted protein degradation, oncology, or immunology.
• Familiarity with AI tools.

Culture & Benefits

• Collaborative, highly team-oriented working environment.
• Solutions- and results-oriented approach.
• Hands-on, resourceful culture open to diverse points of view.
• Close partnership with laboratory, program, and senior scientific teams.