Associate Director, Chemical Engineering

Location: Brisbane, California, United States — onsite; travel up to 25% of the time

Salary: $189,800–$216,700 per year

Company

hirify.global is a clinical-stage biopharmaceutical company developing targeted protein degradation medicines for cancer and inflammatory diseases through an AI-integrated discovery platform.

What you will do

• Lead end-to-end chemical engineering support for bexobrutideg drug substance from late-stage development through commercial launch.
• Design, develop, and optimize scalable small-molecule manufacturing routes, including unit operations, process modeling, equipment selection, and scale-up.
• Oversee CDMO facility and equipment operations, qualification, maintenance, technology transfer, troubleshooting, and manufacturing scale-up.
• Partner with CMC, Quality Assurance, and Global Supply Chain teams to support timely drug substance manufacture and lot release.
• Drive process understanding using critical process parameters, critical quality attributes, control strategies, DoE, and QbD.
• Review manufacturing documentation and regulatory CMC sections, define long-term engineering strategy, and mentor scientists and engineers.

Requirements

• Ph.D. in chemical engineering or a related field with at least 5 years of relevant industrial experience; alternatively, an M.S. with 10 years or a B.S. with 15 years.
• Extensive experience in GMP small-molecule drug substance manufacturing, process development, characterization, equipment evaluation, scale-up, and process validation.
• Knowledge of solid-state properties, polymorphism, and crystallization principles.
• Experience managing third-party drug substance CDMOs, including technology transfer, QbD and DoE studies, clinical supply, registration batches, and commercial launch.
• In-depth knowledge of cGMP, ICH, FDA, and EMA guidelines, with strong communication, collaboration, problem-solving, and conflict-management skills.
• Ability to work onsite in Brisbane, California, and travel up to 25%.

Culture & Benefits

• Collaborative, strongly team-oriented environment.
• Solutions- and results-oriented approach.
• Hands-on, resourceful culture open to diverse points of view.
• Opportunity to provide technical leadership across development, manufacturing, regulatory, and commercial activities.